Quantitative methods that require the measurement of zonediameters can also provide reproducible estimates of the susceptibility ofbacteria to antimicrobial compounds. The zone size should be determined using steve harwell in hospice astandardized method2,5. This procedure uses paper disks impregnatedwith 2 mcg of clindamycin to test the susceptibility of bacteria toclindamycin. The disk diffusion breakpoints are provided in Table 1.

Clindamycin is an antibiotic used to treat bacterial infections including septicemia, pelvic inflammatory disease, abdominal, gynecological, respiratory tract, bone and joint, and skin and skin structure infections. Common side effects of clindamycin include abdominal pain, nausea, vomiting, diarrhea, skin reactions, jaundice, abnormal liver function test results, and others. Use clindamycin during pregnancy only if clearly needed.

Or, you might notice a red rash with swelling of the face, lips or lymph nodes in your neck or under your arms. Medicines that interact with clindamycin may either decrease its effect, affect how long it works, increase side effects, or have less of an effect when taken with clindamycin. An interaction between two medications does not always mean that you must stop taking one of the medications; however, sometimes it does. Speak to your doctor about how drug interactions should be managed. Clindamycin is used to treat a wide variety of bacterial infections. It is an antibiotic that works by stopping the growth of bacteria.This antibiotic treats only bacterial infections.

However, they can also arise in people using topical forms. Historically, anesthesiologists have worried that clindamycin could delay the effectiveness of neuromuscular blocking agents through surgeries. People rarely experience diarrhea or colitis after using clindamycin topically.

  1. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
  2. Doctors use clindamycin to treat a variety of bacterial infections.
  3. It may occur 2 months or more after you stop using this medicine.
  4. Store at room temperature away from light and moisture.

The length of your treatment depends on the type of infection you have and how well you respond to the medication. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Do not take more or less of it or take it more often than prescribed by your doctor. Data from a prospective, randomized, open-label study support the use of clindamycin (in combination with ciprofloxacin) for the outpatient management of neutropenic fever in low-risk cancer patients Rubenstein 1993.

Clindamycin is an antibiotic used for treating serious infections. It is effective again several types of bacteria such as Staphylococcus aureus, Streptococcus pneumoniae, Staphylococcus epidermidis, and Propionibacterium acnes. It reduces the growth of bacteria by interfering with their ability to make proteins. A report of Susceptible (S ) indicatesthat the antimicrobial drug is likely to inhibit growth of the pathogen if theantimicrobial drug reaches the concentration usually achievable at the site ofinfection. A report of Intermediate (I) indicates that the result should beconsidered equivocal, and, if the microorganism is not fully susceptible toalternative, clinically feasible drugs, the test should be repeated.

Commonly used brand name(s)

This medication doesn’t treat viral infections, colds or the flu. Note that this list is not all-inclusive and includes only common medications that may interact with clindamycin. You should refer to the prescribing is it safe to mix antibiotics and alcohol information for clindamycin for a complete list of interactions. Before taking clindamycin, tell your doctor or pharmacist if you are allergic to it; or to lincomycin; or if you have any other allergies.

Use: Labeled Indications

Clindamycin does pass into breast milk and may cause side effects in the nursing baby. If you are breastfeeding while taking this medicine, call your doctor if your baby has diaper rash, redness or white patches in the mouth or throat, stomach discomfort, or diarrhea that is watery or bloody. Let your doctor know if you are breastfeeding before taking clindamycin.

Tell your doctor if you are pregnant or plan to become pregnant during treatment. If you have diarrhea that is watery or bloody, stop using this medicine and call your doctor. If you think there has been an overdose, call your poison control center or get medical care right away. Be ready to tell or show what was taken, how much, and when it happened.

Generic Name(S): clindamycin hcl

Gram-negative bacteria have an additional membrane outside the cell wall that gram-positive bacteria lack. Oxygen is toxic to anaerobic bacteria, while aerobic bacteria can grow in the presence of oxygen because they produce enzymes that detoxify oxygen. If you are using this medication for a longer time, lab and/or medical tests (such as kidney/liver function, blood counts) should be done while you are taking this medication. Older adults may be more sensitive to the effects of this drug, especially diarrhea. If you notice other effects not listed above, contact your doctor or pharmacist. Ask your healthcare professional how you should dispose of any medicine you do not use.

What are the uses for oral clindamycin?

A doctor may recommend clindamycin for certain respiratory infections, lung infections, blood poisoning, and more. In severe liver disease monitor liver function tests periodically; during prolonged therapy monitor CBC, liver and renal function tests periodically. Based on the CDC guidelines for the treatment of malaria, clindamycin, in combination with quinidine or quinine, is effective and recommended for the treatment of malaria. Fertility studies in rats treated orally with up to 300mg/kg/day (approximately 1.6 times the highest recommended adult human dosebased on mg/m²) revealed no effects on fertility or mating ability. This medicine may cause serious allergic reactions, including anaphylaxis.

Take clindamycin until you finish the prescription, even if you feel better. If you stop taking clindamycin too soon or skip doses, your infection may not be completely treated and the bacteria may become resistant to antibiotics. A doctor may prescribe clindamycin in the form of a transvaginal suppository to treat bacterial vaginal infections. Alternatively, they may prescribe a clindamycin lotion for vaginal infections. Pregnant people in their second and third trimesters can use the lotion. It works to treat bacterial infections when penicillin is not an option.